New PIs must be entered in Environment, Health & Safety's (EH&S) database to enable certain research safety authorizations and access EH&S online applications.
Submit a PI Information form to be entered into the EH&S database or to report information changes.
Contact EH&S Biosafety, (858) 534-6059 or 534-0353, for detailed formatting and submission instructions.
Send the required material to EH&S Biosafety:
E-mail: ehsbio@ucsd.edu (preferred method)
Mail Code: 0091
Fax: (858) 534-1510
Submission deadline: To ensure your BUA application is reviewed at the IBC's monthly meeting, submit your complete application no later than the 20th of the month.
Note: BUAs are subject to review, updating, and renewal 1 year after initial approval. Environment, Health & Safety (EH&S) initiates the renewal process by sending the PI a renewal notice.
Amend your currently approved BUA before changing any research variable, or combination of variables, that may carry an increased biohazard risk.
IBC approval is required before beginning work involving any of the following examples (this list is not inclusive):
New infectious agents
New vector systems
Enhanced infectivity
Expression of toxins or oncogenes
Work with human or primate cell lines
Partial genomes increased to more than two-thirds of whole genome
Changes in constructs or systems that result in significantly higher titres
Changing work with non-human systems into work in human systems
New or altered procedures that pose increased risk of aerosol or other type of exposure to biohazards
Any recombinant DNA in vitro, in vivo, and in clinical trials
To amend your BUA:
Follow instructions on the BUA Application welcome screen to amend an active BUA.
Clinical trial BUAs (gene therapy) have special requirements.
Contact EH&S Biosafety, (858) 534-6059 or 534-0353, for consultation and formatting instructions.
Submission deadline: To ensure your BUA application is reviewed at the IBC's monthly meeting, submit your complete application no later than the 20th of the month.